Avoro Capital Advisors LLC

CIK 0001633313 · Q2 2026

13F Equity AUM

$11.1B

+9.6% QoQ

Positions

-4 QoQ

AUM Rank

#477

Top 5%

Skill Alpha (FF)

+13.2%/yr^ns

No Clear Edge

Rank #274 · Top 3%

vs S&P +9.7%/yr (unadj.)

Quarters Tracked

~11 years

Portfolio Concentration

Top 5: 52.6%Top 10: 79.5%Top 20: 98.3%

UTH13.5%

ASCENDIS PHARMA12.2%

KRYS9.6%

MDGL8.8%

ARGX8.3%

ARWR8.3%

KYMR7.7%

RVMD3.9%

CYTK3.8%

CELC3.2%

Others (16)20.5%

HHI (Herfindahl-Hirschman Index) measures portfolio concentration. Low (<1500) = diversified, Moderate (1500-2500), High (>2500) = concentrated bets.

Sector Allocation

Healthcare87.1%

Unclassified12.9%

Portfolio weight by GICS sector based on latest 13F filing. Sectors below 2% are grouped as “Other.”

Position Sizing

Positions: 26Median: 2.91%Avg: 3.85%

0–0.5%

7(2.1%)

0.5–1%

2(1.5%)

1–3%

4(7.5%)

3–5%

6(20.2%)

5%+

7(68.6%)

Count of positions per weight bucket — (%) = combined portfolio weight

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Portfolio Overlap

Shared: 0Unique: 26vs 20 funds

0%Low

Fund positions

Consensus CUSIPs

Jaccard similarity of this fund’s portfolio vs the consensus of top 20 funds by AUM. Low (<15%) = contrarian, Moderate (15-40%), High (>40%) = follows the crowd.

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Position Changes This Quarter

New3Increased9Decreased5Exited7

New Positions

ASCENDIS PHARMA12.2%

+5.1M

HEMAB THERAPEUTICS H…0.6%

+1.9M

SNSE0.3%

+1.4M

Increased

TSHA1.5%

+2.2M(+10%)

DFTX3.0%

+2.2M(+44%)

CYTK3.8%

+1.7M(+50%)

VRDN0.4%

+1.0M(+67%)

AVTX0.4%

+923K(+65%)

QURE2.8%

+768K(+13%)

ARWR8.3%

+656K(+6%)

OCUL1.1%

+225K(+2%)

MDGL8.8%

+15K(+1%)

Decreased

LXEO0.1%

-385,811(-21%)

UTH13.5%

-232,223(-8%)

CELC3.2%

-175,000(-5%)

VERA2.2%

-165,000(-3%)

RVMD3.9%

-47,444(-2%)

Exited

-5,062,500

-12,222,222

-11,430,455

-5,695,000

-2,300,000

-1,200,000

-2,200,000

Quarter-over-quarter changes compared to prior 13F filing. New = first appearance; Exited = no longer held.

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Holdings

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