Darwin Global Management, Ltd.

CIK 0001839209 · Q2 2026

13F Equity AUM

$3.8B

-0.3% QoQ

Positions

-1 QoQ

AUM Rank

#1,725

Top 14%

Skill Alpha (FF)

+12.6%/yr^ns

No Clear Edge

Rank #285 · Top 3%

vs S&P -9.6%/yr (unadj.)

Quarters Tracked

~5 years

Portfolio Concentration

Top 5: 100.0%Top 10: 100.0%Top 20: 100.0%

RVMD54.5%

IM8N17.9%

BLTE12.1%

ABVX9.3%

ROIV6.2%

HHI (Herfindahl-Hirschman Index) measures portfolio concentration. Low (<1500) = diversified, Moderate (1500-2500), High (>2500) = concentrated bets.

Sector Allocation

Healthcare100.0%

Portfolio weight by GICS sector based on latest 13F filing. Sectors below 2% are grouped as “Other.”

Position Sizing

Positions: 5Median: 12.14%Avg: 20.00%

0–0.5%

0(0.0%)

0.5–1%

0(0.0%)

1–3%

0(0.0%)

3–5%

0(0.0%)

5%+

5(100.0%)

Count of positions per weight bucket — (%) = combined portfolio weight

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Portfolio Overlap

Shared: 0Unique: 5vs 20 funds

0%Low

Fund positions

Consensus CUSIPs

Jaccard similarity of this fund’s portfolio vs the consensus of top 20 funds by AUM. Low (<15%) = contrarian, Moderate (15-40%), High (>40%) = follows the crowd.

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Position Changes This Quarter

New0Increased3Decreased2Exited1

Increased

RVMD54.5%

+8.4M(+381%)

ABVX9.3%

+153K(+4%)

BLTE12.1%

+20K(+1%)

Decreased

IM8N17.9%

-10,374,021(-62%)

ROIV6.2%

-50,000(-1%)

Exited

DNTH

-17,357

Quarter-over-quarter changes compared to prior 13F filing. New = first appearance; Exited = no longer held.

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Holdings

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