TCG Crossover Management, LLC

CIK 0001839948 · Q2 2026

13F Equity AUM

$4.2B

+19.0% QoQ

Positions

+5 QoQ

AUM Rank

#965

Top 11%

Skill Alpha (FF)

+46.5%/yr^ns

No Clear Edge

Rank #35 · Top 0.4%

vs S&P +23.8%/yr (unadj.)

Quarters Tracked

~4 years

Portfolio Concentration

Top 5: 41.0%Top 10: 57.5%Top 20: 79.5%

ABVX19.2%

TNGX6.8%

CGON6.3%

COGT4.5%

IMVT4.1%

SYRE4.1%

DNTH3.9%

MIRM3.0%

ZLAB2.8%

AMLX2.7%

Others (44)42.5%

HHI (Herfindahl-Hirschman Index) measures portfolio concentration. Low (<1500) = diversified, Moderate (1500-2500), High (>2500) = concentrated bets.

Sector Allocation

Healthcare97.2%

Unclassified2.8%

Portfolio weight by GICS sector based on latest 13F filing. Sectors below 2% are grouped as “Other.”

Position Sizing

Positions: 54Median: 0.93%Avg: 1.85%

0–0.5%

15(3.3%)

0.5–1%

14(10.9%)

1–3%

18(36.8%)

3–5%

4(16.6%)

5%+

3(32.3%)

Count of positions per weight bucket — (%) = combined portfolio weight

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Portfolio Overlap

Shared: 0Unique: 54vs 20 funds

0%Low

Fund positions

Consensus CUSIPs

Jaccard similarity of this fund’s portfolio vs the consensus of top 20 funds by AUM. Low (<15%) = contrarian, Moderate (15-40%), High (>40%) = follows the crowd.

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Position Changes This Quarter

New12Increased2Decreased9Exited7

New Positions

ZLAB2.8%

+6.1M

AURA1.6%

+9.5M

FIRST TRACKS BIOTHER…1.4%

+2.9M

EDIT0.9%

+11.1M

PHVS0.8%

+1.0M

IFRX0.8%

+14.5M

ALT0.7%

+10.0M

AKTIS ONCOLOGY INC0.5%

+697K

FBRX0.5%

+920K

RESEARCH ALLIANCE CO…0.1%

+500K

Increased

AVTX1.3%

+2.3M(+309%)

MNPR0.5%

+71K(+54%)

Decreased

ALXO0.3%

-7,356,362(-57%)

BHVN0.6%

-2,851,365(-62%)

ARVN0.1%

-1,680,363(-70%)

TNGX6.8%

-1,449,870(-14%)

TRDA0.2%

-1,227,270(-54%)

ABVX19.2%

-473,251(-7%)

LBRX1.1%

-392,179(-21%)

RVMD1.5%

-235,574(-41%)

COGT4.5%

-92,458(-2%)

Exited

-4,286,480

-5,250,000

-403,048

-405,365

-140,411

-181,063

-2,676,580

Quarter-over-quarter changes compared to prior 13F filing. New = first appearance; Exited = no longer held.

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Holdings

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