SR ONE CAPITAL MANAGEMENT, LP

CIK 0001910264 · Q1 2026

13F Equity AUM

$915.4M

+29.6% QoQ

Positions

+1 QoQ

AUM Rank

#2,955

Top 24%

Skill Alpha (FF)

+5.5%/yr^ns

No Clear Edge

Rank #583 · Top 7%

vs S&P -4.2%/yr (unadj.)

Quarters Tracked

~4 years

Portfolio Concentration

Top 5: 74.9%Top 10: 96.5%Top 20: 100.0%

ACLX29.4%

Veradermics, Inc.16.6%

ZBIO10.8%

CRSP10.6%

DSGN7.6%

ORIC6.4%

ALMS4.7%

MLYS4.6%

SPRY3.5%

ORKA2.3%

Others (4)3.5%

HHI (Herfindahl-Hirschman Index) measures portfolio concentration. Low (<1500) = diversified, Moderate (1500-2500), High (>2500) = concentrated bets.

Sector Allocation

Healthcare81.6%

Unclassified18.4%

Portfolio weight by GICS sector based on latest 13F filing. Sectors below 2% are grouped as “Other.”

Position Sizing

Positions: 14Median: 4.67%Avg: 7.14%

0–0.5%

1(0.3%)

0.5–1%

2(1.3%)

1–3%

2(4.2%)

3–5%

3(12.9%)

5%+

6(81.3%)

Count of positions per weight bucket — (%) = combined portfolio weight

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Portfolio Overlap

Shared: 14Unique: 0vs 20 funds

0.2%Low

Fund positions

7,299

Consensus CUSIPs

Jaccard similarity of this fund’s portfolio vs the consensus of top 20 funds by AUM. Low (<15%) = contrarian, Moderate (15-40%), High (>40%) = follows the crowd.

Most Similar Funds

Top 9 benchmark funds with highest portfolio overlap (Jaccard similarity)

GEODE CAPITAL MANAGEMENT, LLC

0.4%

BlackRock, Inc.

0.3%

VANGUARD CAPITAL MANAGEMENT LLC

0.4%

0.4%

0.4%

0.2%

0.2%

BANK OF AMERICA CORP /DE/

0.2%

VANGUARD PORTFOLIO MANAGEMENT LLC

0.4%

Jaccard similarity per fund: shared CUSIPs / (fund A + fund B − shared). Higher values indicate more similar portfolios.

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Position Changes This Quarter

New1Increased0Decreased0Exited0

New Positions

Veradermics, Inc.16.6%

+2.4M

Quarter-over-quarter changes compared to prior 13F filing. New = first appearance; Exited = no longer held.

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Holdings

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