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Held by 341 of 6,047 reporting institutions (95th percentile) — extremely crowded.
Data as of Q2 2026
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Ranked against 25 sector peers with collected financials. Valuation from latest close × latest fiscal-year fundamentals; 13F conviction as of 2026-06-30.
Percentile is “goodness” within the peer set (100 = best). For valuation and leverage that means cheaper / less-levered ranks higher.
| Company | Mkt cap ▼ | P/E | EV/EBITDA | P/S | Rev gr | Gross | Net | ROE | ROIC | Net D/EBITDA | 13F |
|---|---|---|---|---|---|---|---|---|---|---|---|
| CORT | $12.6B | 141.7× | — | 16.5× | 12.8% | 98.3% | 13.1% | 15.4% | 15.4% | -2.6× | 416 |
| BMRN | $11.1B | 31.8× | 21.2× | 3.4× | 12.9% | 77.7% | 10.8% | 5.7% | 5.2% | -1.5× | 545 |
| ELAN | $11.1B | — | — | 2.4× | 6.2% | 55.0% | -4.9% | -3.5% | -2.2% | — | 495 |
| TGTX | $8.3B | 19.6× | 68.7× | 13.5× | 87.3% | 83.7% | 72.6% | 69.0% | 50.0% | 1.4× | 419 |
| IONS | $7.2B | — | — | 7.7× | 33.8% | 98.3% | -40.4% | -78.0% | -17.0% | — | 498 |
| AMRX | $7.1B | 92.3× | 20.7× | 2.3× | 8.0% | 36.9% | 2.4% | -102% | 2.9% | 5.1× | 298 |
| ALKS | $7.0B | 29.2× | 23.5× | 4.8× | -5.2% | 86.7% | 16.4% | 13.3% | 13.3% | -1.4× | 410 |
| RYTM | $6.4B | — | — | 33.7× | 45.8% | 89.7% | -104% | -141% | -79.5% | — | 296 |
| LGND | $6.0B | 49.4× | 78.4× | 22.5× | 60.4% | — | 46.4% | 12.2% | 12.2% | -2.3× | 394 |
| KNSA | $5.9B | 101.0× | 74.3× | 8.7× | 60.1% | 88.5% | 8.7% | 10.4% | 10.4% | -2.1× | — |
| TVTX | $5.4B | — | — | 10.9× | 110% | 97.9% | -5.2% | -22.2% | -22.2% | — | 299 |
| PTCT | $5.3B | 8.2× | 5.1× | 3.1× | 115% | — | 39.4% | -332% | 839% | -0.8× | 362 |
| INDV | $4.2B | 21.8× | 15.9× | 3.4× | 4.3% | 80.2% | 16.9% | -214% | 95.0% | 0.5× | 324 |
| OGN | $3.6B | 19.1× | — | 0.6× | -2.9% | 53.3% | 3.0% | 24.9% | 2.0% | — | 633 |
| ACAD | $3.4B | 8.7× | 30.9× | 3.2× | 11.9% | 91.7% | 36.5% | 31.9% | 31.9% | -1.7× | 341 |
| ARQT | $3.2B | — | — | 8.4× | 91.3% | 90.2% | -4.3% | -8.5% | -5.4% | — | 262 |
| ZLAB | $2.7B | — | — | 5.9× | 15.3% | 58.6% | -38.1% | -24.5% | -19.1% | — | 93 |
| HCM | $2.5B | 27.3× | — | 4.5× | -13.0% | 38.7% | 83.3% | 36.9% | 34.3% | — | 55 |
| SUPN | $2.5B | — | 79.9× | 3.4× | 8.6% | 89.6% | -5.4% | -3.6% | -3.6% | -4.4× | 321 |
| HRMY | $2.3B | 14.6× | — | 2.7× | 21.5% | 77.2% | 18.3% | 18.2% | 15.3% | — | 316 |
| SDGR | $2.3B | — | — | 8.9× | 23.3% | 55.7% | -40.4% | -28.4% | -28.4% | — | 229 |
| BHC | $2.2B | 13.8× | 10.7× | 0.2× | 6.7% | — | 1.5% | -28.3% | 0.8% | 9.7× | 221 |
| PBH | $2.1B | 11.6× | 9.0× | 2.0× | -4.3% | 54.7% | 17.5% | 10.1% | 6.6% | 2.7× | 301 |
| AUPH | $2.1B | 7.7× | 16.3× | 7.4× | 20.4% | 88.5% | — | 49.4% | 49.4% | -0.6× | 271 |
| PRGO | $2.0B | — | — | 0.5× | -2.8% | 35.1% | -33.5% | -48.6% | -21.7% | — | 334 |
Peers = companies sharing ACAD's sector (Pharmaceutical Preparations) with collected SEC financials. Multiples use the most recent end-of-day close and latest fiscal-year fundamentals (trailing, not forward). Missing cells mean the peer never reported that line item, has no collected price, or has a non-positive denominator. Not investment advice.
Total shares institutions bought (green) vs sold (red) each quarter across all holders.
Inferred from quarter-over-quarter change in each fund's 13F position (new stakes count as buys, exits as sells). Not tick-level trades.
What the company returns to shareholders — and whether it's covered by cash.
No dividend to cover. Last year: $0 dividends + $0 buybacks = $0 returned on $105.1M FCF.
Yields use the latest fiscal-year dividends/buybacks over current market cap. Dividends and buybacks from the SEC cash-flow statement; payout coverage vs net income and free cash flow. Educational — not a recommendation.
How management deployed cash over 10 years — and what it earned on reinvestment.
A reinvestment story — most cash went back into growth rather than to shareholders.
Reinvestment has been productive — operating income grew well per dollar put in. Current ROIC on all capital: 32%. Rough measure (includes maintenance capex).
Cash uses aggregated from the SEC cash-flow statement over 10 fiscal years. "Return on reinvestment" is a rough proxy — operating-income change ÷ cumulative CapEx + M&A — and includes maintenance capex. Educational — not a recommendation.
Solve the discounted cash flow backwards, then stress-test the assumptions.
Average free cash flow across the last 2 positive fiscal years (FY2024, FY2025). Smooths the cycle. Stock compensation is NOT charged — it is added back inside operating cash flow.
To be worth $20.11 today, the market must believe free cash flow compounds 11.8%/yr for a decade (off $131.2M on the 3-yr avg basis).
On the basis ($71.6M) the requirement is 20.2%/yr. Shares issued to employees are added back in operating cash flow, so this basis treats them as free.
The market's 11.8% is more optimistic than its 1-yr track record.
Default is 10.5% — this company's computed cost of capital (computed WACC), the same rate the Analysis tab discounts at.
2-stage DCF · 0.17B shares (market data) · net debt -$177.7M
Reverse DCF: rather than guessing a fair value, we solve for the growth the current price implies, then you stress-test the assumptions. Enterprise value of the FCF stream, less net debt, ÷ shares. Educational — not a recommendation.
How much the company owes, how it's trended, and how comfortably it's serviced.
Insufficient EBITDA/debt history.
Green ≤ 1.5× · amber ≤ 3× · red > 3× (leverage relative to cash earnings).
Interest expense isn't separately reported — often netted into “other income (expense), net.”
Cash vs short-term debt unavailable.
Short-term / long-term split not separately reported.
Debt, cash, interest and equity from the SEC balance sheet & income statement. Effective rate = interest ÷ average debt. Educational — not a recommendation.
Top 40 institutional holders — bubble size is position value, color is the move since last quarter. Hover any holder for detail.
Drag any bubble to rearrange · size = dollar value of the position
EOD close · as of 2026-10-05
How a revenue dollar becomes profit — FY2025
Dividends and buybacks are cash paid out, shown here against the same year's profit for scale — not funded from it.
Each value shows its share of revenue below it (common-size).
| Line Item | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | FY2020 | FY2019 | FY2018 | FY2017 | FY2016 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $1.07B 100.0% | $957.8M 100.0% | $726.4M 100.0% | $517.2M 100.0% | $484.1M 100.0% | $441.8M 100.0% | $339.1M 100.0% | $223.8M 100.0% | $124.9M 100.0% | $17.3M 100.0% |
| Cost of Revenue | $89.0M 8.3% | $81.8M 8.5% | $41.6M 5.7% | $10.2M 2.0% | $19.1M 4.0% | $10.2M 2.3% | $11.3M 3.3% | $12.4M 5.5% | $9.1M 7.3% | $3.1M 17.7% |
| Cost of Products | — | — | — | — | — | — | — | — | $9.1M 7.3% | $3.1M 17.7% |
| Gross Profit | — | — | $684.8M 94.3% | $507.1M 98.0% | $473.3M 97.8% | $431.5M 97.7% | $327.7M 96.7% | $211.4M 94.5% | $115.8M 92.7% | $14.3M 82.2% |
| Research & Development | $328.8M 30.7% | $303.2M 31.7% | $351.6M 48.4% | $361.6M 69.9% | $239.4M 49.5% | $319.1M 72.2% | $240.4M 70.9% | $187.2M 83.6% | $149.2M 119.4% | $99.3M 572.9% |
| Selling, General & Admin | $548.9M 51.2% | $488.4M 51.0% | $406.6M 56.0% | $369.1M 71.4% | $396.0M 81.8% | $388.7M 88.0% | $325.6M 96.0% | $265.8M 118.7% | $255.1M 204.2% | $186.5M 1075.9% |
| Total Operating Expenses | $966.7M 90.2% | $727.0M 75.9% | $799.8M 110.1% | $740.8M 143.2% | $654.6M 135.2% | $728.3M 164.9% | $585.6M 172.7% | $471.3M 210.6% | $417.3M 334.1% | $290.1M 1674.1% |
| Operating Income | $104.8M 9.8% | $230.8M 24.1% | -$73.4M -10.1% | -$223.6M -43.2% | -$170.4M -35.2% | -$286.6M -64.9% | -$246.5M -72.7% | -$247.4M -110.6% | -$292.4M -234.1% | -$272.8M -1574.1% |
| Other Income (Expense), net | $2.4M 0.2% | $1.8M 0.2% | $5.1M 0.7% | $3.5M 0.7% | $2.3M 0.5% | -$997K -0.2% | $997K 0.3% | -$1.8M -0.8% | — | — |
| Pretax Income | $138.9M 13.0% | $258.1M 26.9% | -$51.0M -7.0% | -$213.4M -41.3% | -$167.5M -34.6% | -$281.0M -63.6% | -$234.4M -69.1% | -$243.9M -109.0% | -$288.3M -230.8% | -$270.1M -1558.2% |
| Income Tax Expense | -$252.1M -23.5% | $31.6M 3.3% | $10.3M 1.4% | $2.5M 0.5% | $351K 0.1% | $611K 0.1% | $876K 0.3% | $1.3M 0.6% | $1.1M 0.9% | $1.3M 7.7% |
| Net Income | $391.0M 36.5% | $226.0M 23.6% | -$61.0M -8.4% | -$214.0M -41.4% | -$168.0M -34.7% | -$281.6M -63.7% | -$235.3M -69.4% | -$245.2M -109.6% | -$289.4M -231.7% | -$271.4M -1565.9% |
| Per Share | ||||||||||
| EPS (Basic) | $2.32 | $1.37 | -$0.37 | -$1.34 | -$1.05 | -$1.79 | — | — | — | — |
| EPS (Diluted) | $2.30 | $1.36 | -$0.37 | -$1.34 | -$1.05 | -$1.79 | — | — | — | — |
| Weighted Avg Shares (Basic) | 168.4M | 165.7M | 163.8M | 161.7M | 160K | 157K | — | — | — | — |
| Weighted Avg Shares (Diluted) | 169.9M | 166.4M | 163.8M | 161.7M | 160K | 157K | — | — | — | — |
Source: SEC EDGAR XBRL filings (annual, fiscal year). Quarterly flow items are derived from cumulative filings; balance-sheet figures are as-of each period end. Ratios and margins are computed, not reported.
Total return (dividends reinvested) vs the market, from quarter-end prices.
Above 0 = ahead of the S&P 500 since the window start; below 0 = behind. Rising means it's pulling ahead.
How far the stock fell below its prior peak. Deeper, longer drawdowns = a rougher ride to the same return.
Quarter-end, dividend-adjusted (total return). Beta & volatility from quarterly returns (annualized). Benchmark is the S&P 500 (SPY total return). Annual returns compound the quarters ending in each calendar year; the first and last years in a window may be partial. Past performance doesn't predict future results.
EOD close · as of 2026-10-05
Where each multiple sits in its own 14-yr range · 4th pct blended
Dot = today · shaded = middle 50% · line = median. Lower percentile = cheaper vs its own 14-yr history.
Is the profit real, and how strong is the balance sheet?
FY2025 · every deduction from revenue to net income
DuPont — the three levers
ROE 32% against ROIC 32% — 0% of the return on equity comes from leverage and buybacks rather than from the operating business.
Equity is the year-end figure. On average equity over the two year-ends, ROE is 39.9% — the two diverge when buybacks or issuance move equity during the year.
What the company owes vs. what it holds
This shows debt/cash structure and net leverage. The year-by-year maturity schedule is on the Debt & Leverage tab.
Latest year: profit growth vs revenue growth
Profit and sales moved in opposite directions this year.
Each line as % of revenue — the trend in color
| % of revenue | FY2018 | FY2019 | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|---|---|
| Cost of Revenue | 5.5 | 3.3 | 2.3 | 4.0 | 2.0 | 5.7 | 8.5 | 8.3 |
| Gross Profit | 94.5 | 96.7 | 97.7 | 97.8 | 98.0 | 94.3 | — | — |
| R&D | 83.6 | 70.9 | 72.2 | 49.5 | 69.9 | 48.4 | 31.7 | 30.7 |
| SG&A | 118.7 | 96.0 | 88.0 | 81.8 | 71.4 | 56.0 | 51.0 | 51.2 |
| Operating Income | -110.6 | -72.7 | -64.9 | -35.2 | -43.2 | -10.1 | 24.1 | 9.8 |
| Income Tax | 0.6 | 0.3 | 0.1 | 0.1 | 0.5 | 1.4 | 3.3 | -23.5 |
| Net Income | -109.6 | -69.4 | -63.7 | -34.7 | -41.4 | -8.4 | 23.6 | 36.5 |
Green = margin-favorable vs the row's own range · red = unfavorable.
The metrics that matter, over time
A 30-second read on ACAD: price, valuation and headline fundamentals from SEC filings. The four questions at the top of the page are where the judgements live.
Earns 0.98pts above its cost of capital, without much margin of safety.
| Period | ROIC | Cost of capital | Spread |
|---|---|---|---|
| FY2019 | -46.9% | 10.5% (today's — no rate published for this year) | -57.4pts |
| FY2020 | -79.8% | 10.5% (today's — no rate published for this year) | -90.3pts |
| FY2021 | -36.5% | 10.5% (today's — no rate published for this year) | -47.0pts |
| FY2022 | -62.5% | 10.5% (today's — no rate published for this year) | -73.0pts |
| FY2023 | -23.3% | 10.5% (today's — no rate published for this year) | -33.8pts |
| FY2024 | 47.6% | 10.5% (today's — no rate published for this year) | 37.1pts |
| FY2025 | 9.3% | 10.5% (today's — no rate published for this year) | -1.2pts |
| Now | 31.9% | 10.5% | 21.3pts |
| Fiscal year | Gross margin | Operating margin | Net margin |
|---|---|---|---|
| FY2016 | 82.2% | -1574.1% | -1565.9% |
| FY2017 | 92.7% | -234.1% | -231.7% |
| FY2018 | 94.5% | -110.6% | -109.6% |
| FY2019 | 96.7% | -72.7% | -69.4% |
| FY2020 | 97.7% | -64.9% | -63.7% |
| FY2021 | 97.8% | -35.2% | -34.7% |
| FY2022 | 98.0% | -43.2% | -41.8% |
| FY2023 | 94.3% | -10.1% | -8.4% |
| FY2024 | 91.5% | 24.1% | 23.6% |
| FY2025 | 91.7% | 9.8% | 36.5% |
Return on equity (32%) and return on invested capital (32%) are within a couple of points in FY2025, so the headline return is the operating return — there is no meaningful leverage effect to strip out.
The spread is 0.98pts and would invert under a ±2% move in WACC, so the verdict rests on the cost-of-capital assumption rather than on the business.
Fewer than three profitable years with a cash flow statement, so cash conversion cannot be judged.
No material counter-signal in the checked set: FCF / net income over 3 and 5 years, Sloan accruals, SBC as a share of revenue, SBC as a share of operating cash flow, SBC-adjusted free cash flow, free cash flow per diluted share, buybacks against SBC issued, capex vs depreciation, free cash flow against revenue, share count since the first year on file, cash conversion cycle (DSO, DIO, DPO), receivables growth against revenue growth.
Missing from our data, so excluded from this answer: 3 years of cash flow.
Debt is present but there is no positive EBITDA or no reported interest expense, so coverage cannot be measured.
Balance sheet at 2025-12-31. Undrawn revolving credit is not shown: the tag is collected but not yet mapped through to the API.
No material counter-signal in the checked set: net debt / EBITDA, interest coverage, stressed coverage, maturity schedule vs cash and one year of FCF, liquidity ratios.
Missing from our data, so excluded from this answer: interest_expense.
At $19.95, free cash flow must compound 11.92%/yr for 10 years. It has no positive compounding record to compare against.
The implied rate of 11.92% has not been achieved in any of the last 1 years.