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Held by 327 of 5,944 reporting institutions (95th percentile) — extremely crowded.
Data as of Q1 2026
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Total shares institutions bought (green) vs sold (red) each quarter across all holders.
Inferred from quarter-over-quarter change in each fund's 13F position (new stakes count as buys, exits as sells). Not tick-level trades.
Ranked against 1111 sector peers with collected financials. Valuation from latest close × latest fiscal-year fundamentals; 13F conviction as of 2026-03-31.
Percentile is “goodness” within the peer set (100 = best). For valuation and leverage that means cheaper / less-levered ranks higher.
| Company | Mkt cap ▼ | P/E | EV/EBITDA | P/S | Rev gr | Gross | Net | ROE | ROIC | Net D/EBITDA | 13F |
|---|---|---|---|---|---|---|---|---|---|---|---|
| LLY | $1.05T | 51.0× | — | 16.1× | 44.7% | 83.0% | 31.7% | 77.8% | 29.9% | — | 4,193 |
| AKTX | $679.0B | — | — | — | — | — | — | -61.1% | -61.1% | — | 1 |
| JNJ | $620.1B | 23.4× | — | 6.6× | 6.0% | 67.9% | 28.5% | 32.9% | 20.7% | — | 4,451 |
| ABBV | $435.4B | 104.3× | 31.4× | 7.1× | 8.6% | 70.2% | 6.9% | -129% | 6.6% | 4.2× | 3,895 |
| UNH | $374.0B | 31.2× | 21.4× | 0.8× | 11.8% | 88.7% | 2.7% | 12.0% | 6.8% | 3.9× | 2,891 |
| BDRX | $359.1B | — | — | — | — | — | — | — | — | — | 7 |
| MRK | $321.1B | 17.6× | — | 4.9× | 1.3% | 74.8% | 28.1% | 34.7% | 17.9% | — | 3,594 |
| NVSEF | $289.9B | — | — | — | — | — | — | — | — | — | 2 |
| AZN | $250.4B | — | — | — | — | — | — | — | — | — | 1,248 |
| AMGN | $219.7B | 28.7× | 18.3× | 6.0× | 10.0% | 67.2% | 21.0% | 89.1% | 13.1% | 3.5× | 3,014 |
| TMO | $217.8B | 32.6× | 28.5× | 4.9× | 3.9% | — | 15.1% | 12.6% | 7.0% | 4.9× | 2,481 |
| ABT | $183.9B | 28.4× | 19.5× | 4.2× | 5.7% | 56.4% | 14.7% | 12.5% | 10.5% | 1.0× | 2,964 |
| GILD | $163.5B | 19.4× | 18.1× | 5.5× | 2.4% | 78.8% | 28.9% | 37.5% | 17.9% | 2.4× | 2,218 |
| PFE | $146.7B | 19.0× | — | 2.3× | -1.6% | 74.3% | 12.4% | 9.0% | 5.1% | — | 2,838 |
| DHR | $141.1B | 39.5× | 29.3× | 5.7× | 2.9% | 59.1% | 14.7% | 6.9% | 5.1% | 3.4× | 2,083 |
| ISRG | $133.2B | 47.7× | 36.6× | 13.2× | 20.5% | 66.0% | 28.4% | 16.0% | 16.0% | — | 2,190 |
| SYK | $128.8B | 40.1× | 21.8× | 5.1× | 11.2% | 64.0% | 12.9% | 14.5% | 8.5% | 2.5× | 2,196 |
| CVS | $126.0B | 71.3× | 12.7× | 0.3× | 7.8% | 45.0% | 0.4% | 2.4% | 2.4% | 0.0× | 1,795 |
| VRTX | $123.1B | 31.6× | 26.9× | 10.3× | 8.9% | 86.2% | 32.9% | 21.2% | 21.2% | — | 1,609 |
| MDT | $110.1B | 23.1× | 11.7× | 3.0× | 8.4% | 65.0% | 13.2% | 9.7% | 9.4% | 0.2× | 2,114 |
| GLAXF | $106.9B | — | — | — | — | — | — | — | — | — | 5 |
| MCK | $102.7B | 22.9× | 16.2× | 0.3× | 12.4% | 3.6% | 1.2% | -219% | 109% | 1.0× | 1,946 |
| SNYNF | $101.3B | — | — | — | — | — | — | — | — | — | 5 |
| HCA | $92.0B | 14.5× | — | 1.2× | 7.1% | — | 9.0% | -113% | 16.8% | — | 1,346 |
| ELV | $86.4B | 15.5× | 14.8× | 0.4× | 12.5% | 89.4% | 2.8% | 12.9% | 7.6% | 4.2× | 1,397 |
| ACAD | $4.9B | 12.5× | 44.7× | 4.6× | 11.9% | 91.7% | 36.5% | 31.9% | 31.9% | — | 327 |
Peers = companies sharing ACAD's sector (Healthcare) with collected SEC financials. Multiples use the most recent end-of-day close and latest fiscal-year fundamentals (trailing, not forward). Missing cells mean the peer never reported that line item, has no collected price, or has a non-positive denominator. Not investment advice.
Top 40 institutional holders — bubble size is position value, color is the move since last quarter. Hover any holder for detail.
Drag any bubble to rearrange · size = dollar value of the position
How management deployed cash over 10 years — and what it earned on reinvestment.
A reinvestment story — most cash went back into growth rather than to shareholders.
Reinvestment has been productive — operating income grew well per dollar put in. Current ROIC on all capital: 32%. Rough measure (includes maintenance capex).
Cash uses aggregated from the SEC cash-flow statement over 10 fiscal years. "Return on reinvestment" is a rough proxy — operating-income change ÷ cumulative CapEx + M&A — and includes maintenance capex. Educational — not a recommendation.
How much the company owes, how it's trended, and how comfortably it's serviced.
Insufficient EBITDA/debt history.
Green ≤ 1.5× · amber ≤ 3× · red > 3× (leverage relative to cash earnings).
Interest expense isn't separately reported — often netted into “other income (expense), net.”
Cash vs short-term debt unavailable.
Short-term / long-term split not separately reported.
Debt, cash, interest and equity from the SEC balance sheet & income statement. Effective rate = interest ÷ average debt. Educational — not a recommendation.
EOD close · as of 2026-08-05 · 15d old
How a revenue dollar becomes profit — FY2025
Each value shows its share of revenue below it (common-size).
| Line Item | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | FY2020 | FY2019 | FY2018 | FY2017 | FY2016 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $1.07B 100.0% | $957.8M 100.0% | $726.4M 100.0% | $517.2M 100.0% | $484.1M 100.0% | $441.8M 100.0% | $339.1M 100.0% | $223.8M 100.0% | $124.9M 100.0% | $17.3M 100.0% |
| Cost of Revenue | $89.0M 8.3% | $81.8M 8.5% | $41.6M 5.7% | $10.2M 2.0% | $19.1M 4.0% | $10.2M 2.3% | $11.3M 3.3% | $12.4M 5.5% | $9.1M 7.3% | $3.1M 17.7% |
| Cost of Products | — | — | — | — | — | — | — | — | $9.1M 7.3% | $3.1M 17.7% |
| Gross Profit | — | — | $684.8M 94.3% | $507.1M 98.0% | $473.3M 97.8% | $431.5M 97.7% | $327.7M 96.7% | $211.4M 94.5% | $115.8M 92.7% | $14.3M 82.2% |
| Research & Development | $328.8M 30.7% | $303.2M 31.7% | $351.6M 48.4% | $361.6M 69.9% | $239.4M 49.5% | $319.1M 72.2% | $240.4M 70.9% | $187.2M 83.6% | $149.2M 119.4% | $99.3M 572.9% |
| Selling, General & Admin | $548.9M 51.2% | $488.4M 51.0% | $406.6M 56.0% | $369.1M 71.4% | $396.0M 81.8% | $388.7M 88.0% | $325.6M 96.0% | $265.8M 118.7% | $255.1M 204.2% | $186.5M 1075.9% |
| Total Operating Expenses | $966.7M 90.2% | $727.0M 75.9% | $799.8M 110.1% | $740.8M 143.2% | $654.6M 135.2% | $728.3M 164.9% | $585.6M 172.7% | $471.3M 210.6% | $417.3M 334.1% | $290.1M 1674.1% |
| Operating Income | $104.8M 9.8% | $230.8M 24.1% | -$73.4M -10.1% | -$223.6M -43.2% | -$170.4M -35.2% | -$286.6M -64.9% | -$246.5M -72.7% | -$247.4M -110.6% | -$292.4M -234.1% | -$272.8M -1574.1% |
| Other Income (Expense), net | $2.4M 0.2% | $1.8M 0.2% | $5.1M 0.7% | $3.5M 0.7% | $2.3M 0.5% | -$997K -0.2% | $997K 0.3% | -$1.8M -0.8% | — | — |
| Pretax Income | $138.9M 13.0% | $258.1M 26.9% | -$51.0M -7.0% | -$213.4M -41.3% | -$167.5M -34.6% | -$281.0M -63.6% | -$234.4M -69.1% | -$243.9M -109.0% | -$288.3M -230.8% | -$270.1M -1558.2% |
| Income Tax Expense | -$252.1M -23.5% | $31.6M 3.3% | $10.3M 1.4% | $2.5M 0.5% | $351K 0.1% | $611K 0.1% | $876K 0.3% | $1.3M 0.6% | $1.1M 0.9% | $1.3M 7.7% |
| Net Income | $391.0M 36.5% | $226.0M 23.6% | -$61.0M -8.4% | -$214.0M -41.4% | -$168.0M -34.7% | -$281.6M -63.7% | -$235.3M -69.4% | -$245.2M -109.6% | -$289.4M -231.7% | -$271.4M -1565.9% |
| Per Share | ||||||||||
| EPS (Basic) | $2.32 | $1.37 | $-0.37 | $-1.34 | $-1.05 | $-1.79 | — | — | — | — |
| EPS (Diluted) | $2.30 | $1.36 | $-0.37 | $-1.34 | $-1.05 | $-1.79 | — | — | — | — |
| Weighted Avg Shares (Basic) | 168.4M | 165.7M | 163.8M | 161.7M | 160K | 157K | — | — | — | — |
| Weighted Avg Shares (Diluted) | 169.9M | 166.4M | 163.8M | 161.7M | 160K | 157K | — | — | — | — |
Source: SEC EDGAR XBRL filings (annual, fiscal year). Quarterly flow items are derived from cumulative filings; balance-sheet figures are as-of each period end. Ratios and margins are computed, not reported.
Solve the discounted cash flow backwards, then stress-test the assumptions.
To be worth $28.80 today, the market must believe free cash flow compounds 20.4%/yr for a decade (off $93M normalized FCF).
The market's 20.4% is more conservative than its 2-yr track record.
2-stage DCF · 0.17B shares · net debt -$178M
mean 405.4% · volatility σ 620% · implied rate exceeded in 1/2 yrs
Central path = implied 20.4%/yr growth; shaded band = ±1σ (620%) of this company's historical FCF volatility, widening with time. The wider the band, the less certain the growth.
Reverse DCF: rather than guessing a fair value, we solve for the growth the current price implies, then you stress-test the assumptions. Enterprise value of the FCF stream, less net debt, ÷ shares. Educational — not a recommendation.
Is the value real, and is the business safe? Academic scores + earnings quality + solvency, from SEC filings.
5/8 of the 9 checks — 1 couldn't be scored (see above), so the score is out of the 8 with data.
Safe > 2.99 · grey 1.81–2.99 · distress < 1.81
Eight indices comparing this year to last (receivables, margins, asset quality, growth, accruals, leverage). Above −1.78 suggests possible manipulation; below −2.22 is clean.
A screen, not proof — high growth alone can raise it.
Cash conversion lags reported earnings — watch accruals. Lower/negative accruals = higher quality (Sloan).
Coverage data unavailable.
F-Score (0–9 fundamental momentum), Altman Z (distress risk), and Beneish M (earnings-manipulation screen) are academic models computed from the SEC filings. Screens and context — educational, not recommendations.
What the company returns to shareholders — and whether it's covered by cash.
No dividend to cover. Last year: $0 dividends + $0 buybacks = $0 returned on $105M FCF.
Yields use the latest fiscal-year dividends/buybacks over current market cap. Dividends and buybacks from the SEC cash-flow statement; payout coverage vs net income and free cash flow. Educational — not a recommendation.
Total return (dividends reinvested) vs the market, from quarter-end prices.
Above 0 = ahead of the S&P 500 since the window start; below 0 = behind. Rising means it's pulling ahead.
How far the stock fell below its prior peak. Deeper, longer drawdowns = a rougher ride to the same return.
Quarter-end, dividend-adjusted (total return). Beta & volatility from quarterly returns (annualized). Benchmark is the S&P 500 (SPY total return). Annual returns compound the quarters ending in each calendar year; the first and last years in a window may be partial. Past performance doesn't predict future results.
EOD close · as of 2026-08-05
No material risks flagged.
Where each multiple sits in its own 14-yr range · 10th pct blended
Dot = today · shaded = middle 50% · line = median. Lower percentile = cheaper vs its own 14-yr history.
Is the profit real, and how strong is the balance sheet?
FY2025 · every deduction from revenue to net income
DuPont — the three levers
Returns are margin-driven, not leverage-driven — higher quality.
What the company owes vs. what it holds
Year-by-year maturities aren't in SEC companyfacts (footnote-only), so this shows the debt/cash structure and net leverage instead.
Latest year: profit growth vs revenue growth
Profit and sales moved in opposite directions this year.
Each line as % of revenue — the trend in color
| % of revenue | FY2018 | FY2019 | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|---|---|
| Cost of Revenue | 5.5 | 3.3 | 2.3 | 4.0 | 2.0 | 5.7 | 8.5 | 8.3 |
| Gross Profit | 94.5 | 96.7 | 97.7 | 97.8 | 98.0 | 94.3 | — | — |
| R&D | 83.6 | 70.9 | 72.2 | 49.5 | 69.9 | 48.4 | 31.7 | 30.7 |
| SG&A | 118.7 | 96.0 | 88.0 | 81.8 | 71.4 | 56.0 | 51.0 | 51.2 |
| Operating Income | -110.6 | -72.7 | -64.9 | -35.2 | -43.2 | -10.1 | 24.1 | 9.8 |
| Income Tax | 0.6 | 0.3 | 0.1 | 0.1 | 0.5 | 1.4 | 3.3 | -23.5 |
| Net Income | -109.6 | -69.4 | -63.7 | -34.7 | -41.4 | -8.4 | 23.6 | 36.5 |
Green = margin-favorable vs the row's own range · red = unfavorable.
The metrics that matter, over time
A 30-second read on ACAD: price, valuation, headline fundamentals, and an auto-generated scorecard from SEC filings. Flags are rule-based signals, not recommendations.